C1qTNF5/CTRP5 Antibody (A14-A)

Western Blot: C1qTNF5/CTRP5 Antibody (A14-A) [NBP1-30131] - Mouse recombinant CTRP5 protein.

• Reactivity: Hu, Mu
• Applications: WB, ELISA
• Clone: A14-A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

C1qTNF5/CTRP5 Antibody (A14-A) Summary

• Description: This antibody is immunoaffinity purified with immunogenic peptide as a ligand.
• Immunogen: Peptide close to the amino terminus of human C1qTNF5/CTRP5. Antibody recognizes the epitope located between Lys109 - Ala121.
• Epitope: Lys109 - Ala121
• Specificity: This antibody is specific for the amino terminus of CTRP5
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: C1QTNF5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:50000-1:100000
  • Western Blot 1:5000
• Application Notes: For western blots, incubate the membrane with antibody diluted in blocking buffer 2 hours at room temperature. Western immunoblotting solutions: Wash buffer: 1x Tris Buffered Saline (TBS); 0.2% Triton X-100. Blocking buffer: 1xTBS; 0.2% Triton X-100; 8% nonfat dry milk.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Tris/HCl (pH 8.0) and 10 mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Alternate Names for C1qTNF5/CTRP5 Antibody (A14-A)

• C1q and tumor necrosis factor related protein 5
• C1qTNF5
• Complement C1q Tumor Necrosis Factor-Related Protein 5 Precursor Variant 3
• CTRP5
• CTRP5LORDDKFZp586B0621
• LORD 6
• Myonectin 3

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C1QTNF5
• Entrez:
  • 114902(Human)
• Uniprot:
  • Q9BXJ0()