Canine C-Reactive Protein/CRP ELISA Kit (Colorimetric) Summary
Description |
CRP (Dog) ELISA Kit is a highly sensitive two-site enzyme-linked immunoassay for the quantitative determination of CRP in dog biological samples. |
Standard Curve Range |
3.125 to 200 ng/mL |
Sensitivity |
1.196 |
Assay Type |
Two-site enzyme-linked immunoassay |
Sample Volume |
100 uL |
Kit Type |
ELISA Kit (Colorimetric) |
Gene |
CRP |
Applications/Dilutions
Packaging, Storage & Formulations
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Canine C-Reactive Protein/CRP ELISA Kit (Colorimetric)
Background
C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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