c-Maf Antibody - BSA Free

Western Blot: c-Maf Antibody [NB600-267] - Nuclear extract (6 ug) from HeLa cells transfected with empty vector or expression constructs for mouse MafA, mouse MafB or mouse cMaf. Antibody used at 0.4 ug/ml.

• Reactivity: Mu, Bv
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

c-Maf Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit c-Maf Antibody - BSA Free (NB600-267) is a polyclonal antibody validated for use in WB. Anti-c-Maf Antibody: Cited in 6 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 150 and 200 of mouse v-maf musculoaponeurotic fibrosarcoma oncogene homolog (c-Maf) using the numbering given in entry NP_001020748.2 (GeneID 17132).
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAF
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for c-Maf Antibody - BSA Free

• Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene
• CCA4
• c-maf proto-oncogene
• cMaf
• c-Maf
• MAF2
• MGC71685
• Proto-oncogene c-Maf
• T lymphocyte c-maf long form
• transcription factor Maf
• v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog
• v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
• V-maf musculoaponeurotic fibrosarcoma oncogene homolog

Background

c-Maf is part of the Maf family of transcription factors that possess a conserved basic region and a leucine zipper domain that mediate DNA and protein-protein binding and plays an important role in tissue-specific gene regulation and cell differentiation. c-Maf is a transcriptional activator of interleukin 4 and 10 in T-cells, and is involved in lens fiber cell differentiation. c-Maf translocation has been observed in human multiple myeloma and may be oncogenic.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for c-Maf Antibody (NB600-267)(6)

Publications using NB600-267

• Worthy AE, Anderson JT, Lane AR et Al. Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity Elife 2024-11-28 [PMID: 39607843]
• Xie Q, Cvekl A. The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops. J Biol Chem 2011-12-01 [PMID: 21998302]
• Katz LS, Gosmain Y, Marthinet E et al. Pax6 regulates the proglucagon processing enzyme PC2 and its chaperone 7B2. Mol Cell Biol 2009-04-01 [PMID: 19223471]
• Gosmain Y, Avril I, Mamin A et al. Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression. J Biol Chem 2007-11-01 [PMID: 17901057]
• Nishimura W, Kondo T, Salameh T et al. A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol 2006-05-01 [PMID: 16580660]
• Cao S, Liu J, Song L et al. The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J Immunol 2005-03-01 [PMID: 15749884]

Bioinformatics

• Gene Symbol: MAF
• Entrez:
  • 17132(Mouse)
• Uniprot:
  • P54843(Mouse)