BTBD12 Antibody

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Immunoprecipitation: BTBD12 Antibody [NBP1-28679] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-BTBD12 antibody NBP1-28679 used for IP at 10 ug/mg ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

BTBD12 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1650 and 1700 of human BTB (POZ) domain containing 12 using the numbering given in entry NP_115820.2 (GeneID 84464).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLX4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 2 - 10 ug/mg lysate
Application Notes
IHC use reported in literature (see Holloway JK, et al).
Publications
Read Publications using NBP1-28679.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BTBD12 Antibody

  • BTB (POZ) domain containing 12
  • BTB/POZ domain-containing protein 12
  • BTBD12structure-specific endonuclease subunit SLX4
  • KIAA1784MUS312
  • KIAA1987FANCP
  • SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

Background

BTBD12 (BTBD12 domain-containing protein 12) has been identified as the human ortholog of the yeast Slx4p and drosophila MUS312 DNA repair factors. BTBD12 is an ATM/ATR checkpoint substrate that functions as part of a Holliday junction resolvase and is important for DNA interstrand crosslink repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: IP, WB (-)

Publications for BTBD12 Antibody (NBP1-28679)(3)

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Product General Protocols

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FAQs for BTBD12 Antibody (NBP1-28679). (Showing 1 - 1 of 1 FAQs).

  1. What concentration do you recommend using this antibody at for probing Westerns?
    • Please note that our product BTBD12 Antibody (NBP1-28679) is recommended for immunoprecipitation (IP), but not for Western blot - the minus sign next to 'WB' on the datasheet denotes 'Western blot - negative' and means that testing has indicated that this product is not suitable for western blot.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SLX4
Entrez
Uniprot