SLX4 Products

Antibodies
SLX4 Antibody - Azide and BSA ...
SLX4 Antibody - Azide and BSA Free
H00084464-B01P
Species: Hu, Mu
Applications: WB, ICC/IF, Mycoplasma
Host: Mouse Polyclonal
Proteins
SLX4 Recombinant Protein Anti ...
SLX4 Recombinant Protein Antigen
NBP2-58436PEP
Species: Hu
Applications: AC
SLX4 Recombinant Protein Anti ...
SLX4 Recombinant Protein Antigen
NBP2-39070PEP
Species: Hu
Applications: AC

Description

BTBD12 (BTBD12 domain-containing protein 12) has been identified as the human ortholog of the yeast Slx4p and drosophila MUS312 DNA repair factors. BTBD12 is an ATM/ATR checkpoint substrate that functions as part of a Holliday junction resolvase and is important for DNA interstrand crosslink repair.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 84464
Alternate Names
  • BTB (POZ) domain containing 12
  • BTB/POZ domain-containing protein 12
  • BTBD12structure-specific endonuclease subunit SLX4
  • KIAA1784MUS312
  • KIAA1987FANCP
  • SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

Related SLX4 Blog Posts

Check out the latest blog posts on SLX4.
FANCD2: A big component of the DNA repair crew
The genetic disorder known as Fanconi anemia (FANC) is a heterogeneous, autosomal-recessive cancer susceptibility condition characterized by a wide array of symptoms. These include congenital malformations, progressive bone marrow failure, DNA-damage ...    Read more.
FANCD2 (Fanconi anemia subunit D2 protein)
Fanconi anemia (FANC) is a rare, autosomal-recessive genetic disorder that is a heterogeneous cancer susceptibility condition that manifests with a wide range of symptoms such as congenital malformations, deteriorating bone marrow failure, DNA-dama...    Read more.
Read more SLX4 related blogs.