Recombinant Human BMP-3b/GDF-10 Protein

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SDS-Page: Recombinant Human BMP-3b/GDF-10 Protein [NBC1-28772] - GDF-10, 12.5 kDa (111aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

Recombinant Human BMP-3b/GDF-10 Protein Summary

Description
An un-tagged recombinant protein corresponding to the amino acids 369-478 of Human BMP-3b/GDF-10

Source: E.coli

Amino Acid Sequence: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
GDF10
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
12.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10mM Sodium citrate (pH 3.5) containing 1mM DTT, 40% glycerol, 0.1M NaCl
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human BMP-3b/GDF-10 Protein

  • BIP
  • BMP3b
  • BMP-3b
  • bone morphogenetic protein 3B
  • Bone-inducing protein
  • GDF10
  • GDF-10
  • growth differentiation factor 10
  • Growth/differentiation factor 10

Background

GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol GDF10
Entrez