Recombinant Human BMP-3b/GDF-10 Protein

Product Discontinued

Recombinant Human BMP-3b/GDF-10 Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 369-478 of Human BMP-3b/GDF-10
  
  

  Source: E.coli

  Amino Acid Sequence: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: GDF10
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 12.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 10 mM Sodium Citrate buffer (pH 3.5), 1 mM DTT, 40% glycerol, 0.1 M NaCl
• Preservative: No Preservative
• Concentration: 0.25 mg/ml
• Purity: >95% pure by SDS-PAGE

Alternate Names for Recombinant Human BMP-3b/GDF-10 Protein

• BIP
• BMP3b
• BMP-3b
• bone morphogenetic protein 3B
• Bone-inducing protein
• GDF10
• GDF-10
• growth differentiation factor 10
• Growth/differentiation factor 10

Background

GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Recombinant GDF10 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: GDF10