Betacellulin/BTC Antibody [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB, IHC, B/N
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 669

Betacellulin/BTC Antibody [Janelia Fluor® 669] Summary

• Immunogen: E. coli-derived recombinant human Betacellulin
  Asp32-Tyr111
  Accession # P35070
• Specificity: Detects Betacellulin/BTC in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: BTC
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Neutralization
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Betacellulin/BTC Antibody [Janelia Fluor® 669]

• Betacellulin
• BTC
• probetacellulin

Background

Betacellulin (BTC) is a member of the EGF (epidermal growth factor) family. The transmembrane BTC precursor undergoes proteolytic cleavage, releasing the BTC ligand. It binds to both EGFR/ErbB-1 and ErbB-4 receptor tyrosine kinases. Betacellulin has been found to affect influence various cell types, such as neural stem cells (NSCs), mesenchymal stem cells (MSCs), pancreatic beta cells, retinal pigment epithelial cells and smooth muscle cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BTC