Immunocytochemistry/ Immunofluorescence: beta-III Tubulin Antibody [NB100-1612] - Dissociated cell culture of a neonatal mouse brain showing beta-III Tubulin (green staining) of neurons. These cultures were ...read more
The synthetic peptides used as an immunogen are shared between human and rat protein sequences.
Packaging, Storage & Formulations
Store at 4C in the dark.
10mM Sodium PBS (0.9% isotonic, w/v, pH 7.2)
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for beta-III Tubulin Antibody
Class III beta-tubulin
Tubulin Beta 3
tubulin beta-3 chain
Tubulin beta-4 chain
tubulin, beta 3
Beta-III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells. In adult tissues, the distribution of beta III tubulin is almost exclusively neuron-specific.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for beta-III Tubulin Antibody (NB100-1612). (Showing 1 - 2 of 2 FAQs).
I would like to find out the isotype information for Catalog Number NB100-1612. Is it IgG or IgY? What kind of secondary antibody should I use?
Our tubulin beta 3 antibody with catalogue number NB100-1612 is a chicken polyclonal, of the isotype IgY. You can see our relevant secondary antibodies for the detection of chicken IgY at the following link: View Secondary Antibodies
Do you know if the beta-III tubulin antibody (Cat NB100-1612) has been successfully used for ELISA?
Our tubulin beta 3 antibody with catalogue number NB100-1612 has not yet been validated for ELISA.
Beta Tubulin III and neurogenesis Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network. While general tubulins play a role in a wide range of cellular pr... Read full blog post.
Beta III tubulin The Beta III tubulin protein is abundantly present in both the central and peripheral nervous systems (CNS and PNS), where it is predominantly expressed during fetal and postnatal development. In cerebellar and sympathoadrenal neurogenesis, Beta III d... Read full blog post.
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