Beta Hydroxysteroid Dehydrogenase Antibody [Biotin]

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Biotin

Beta Hydroxysteroid Dehydrogenase Antibody [Biotin] Summary

• Immunogen: hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 2. (Uniprot# P26439)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HSD3B2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Beta Hydroxysteroid Dehydrogenase Antibody [Biotin]

• 3 beta-HSD type II
• 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
• 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II
• 3-beta-HSD II
• delta 5-delta 4-isomerase type II
• HSD3B
• HSDB
• HSDB3B
• hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2,3-beta-hydroxy-Delta(5)-steroid dehydrogenase
• progesterone reductase
• SDR11E2
• short chain dehydrogenase/reductase family 11E, member 2,3-beta-hydroxy-5-ene steroid dehydrogenase

Background

The protein encoded by the Beta Hydroxysteroid Dehydrogenases gene is a bifunctional enzyme that catalyzes the oxidative conversion ofdelta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in thebiosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads.Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternativelyspliced transcript variants have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HSD3B2