Bestrophin 1 Antibody (E6-6) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Po, Ca, Pm, Rt(-), PmSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
E6-6
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Bestrophin 1 Antibody (E6-6) [DyLight 350] Summary

Immunogen
Synthetic peptide conjugated to KLH corresponding to the C-terminus of human Bestrophin 1 (KDHMDPYWALENRDEAHS) [Uniprot: O76090]
Specificity
Bestrophin (E6-6)
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
BEST1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human, Primate, Porcine reactivity reported in scientific literature (PMID: 11050159).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Bestrophin 1 Antibody (E6-6) [DyLight 350]

  • ARB
  • Best disease
  • BEST
  • bestrophin 1
  • bestrophin-1
  • BMD
  • TU15B
  • vitelliform macular dystrophy 2
  • Vitelliform macular dystrophy protein 2
  • VMD2RP50

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Bestrophin 1 Antibody (NB300-164UV) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB300-164AF350
Alexa Fluor 405 NB300-164AF405
Alexa Fluor 488 NB300-164AF488
Alexa Fluor 532 NB300-164AF532
Alexa Fluor 647 NB300-164AF647
Alexa Fluor 700 NB300-164AF700
Alexa Fluor 750 NB300-164AF750
Biotin NB300-164B
DyLight 350 NB300-164UV
DyLight 405 NB300-164V
DyLight 488 NB300-164G
DyLight 550 NB300-164R
DyLight 594 NB300-164DL594
DyLight 650 NB300-164C
DyLight 680 NB300-164FR
DyLight 755 NB300-164IR
FITC NB300-164F
HRP NB300-164H
Janelia Fluor 549 NB300-164JF549
Janelia Fluor 646 NB300-164JF646

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Bioinformatics Tool for Bestrophin 1 Antibody (NB300-164UV)

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Blogs on Bestrophin 1.

Vision Infographic: Do you see how I see?
Vision involves several parts of the eye processing light which send signals to the brain via the optic nerve to process information. Learn more about the vision process and related ocular proteins in the infographic below. Novus Biological...  Read full blog post.

Bestrophin 1: Implications in Progressive Vision Loss
The human Bestrophin family has four members, Best1, Best2, Best3 and Best4. These transmembrane proteins can function as chloride channels, and can also regulate calcium channels (1). The Bestrophins all have a conserved domain which begins at the N-...  Read full blog post.

"I can see clearly now": Targeting Bestrophin 1 to treat Bestrophinopathies
Encoded by the VMD2 gene on chromosome 11q13 Bestrophin 1 is the prototypic member of the RFP family of proteins which are more commonly called "bestrophins". The protein family was originally identified in Caenorhabditis elegans based on a conserved...  Read full blog post.

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Bioinformatics

Gene Symbol BEST1