BCMA/TNFRSF17 Antibody [Phycoerythrin]


RPMI 8226 human multiple myeloma cell line was stained with Goat Anti-Human BCMA/TNFRSF17 PE‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB193P, filled histogram) or isotype control ...read more

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Reactivity HuSpecies Glossary
Applications Flow

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BCMA/TNFRSF17 Antibody [Phycoerythrin] Summary

Mouse myeloma cell line NS0-derived recombinant human BCMA/TNFRSF17
Accession # Q6PE46
Detects human BCMA in ELISAs and Western blots. In sandwich ELISAs, less than 0.1% cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhTACI, and recombinant mouse BCMA is observed.
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  • Flow Cytometry 10 uL/10^6 cells
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FAB193P in the following applications:

Packaging, Storage & Formulations

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Supplied in a saline solution containing BSA and Sodium Azide.
Sodium Azide


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BCMA/TNFRSF17 Antibody [Phycoerythrin]

  • B cell maturation antigen
  • B-cell maturation protein
  • BCMA
  • BCMAtumor necrosis factor receptor superfamily member 17
  • BCMB-cell maturation factor
  • CD269 antigen
  • CD269
  • TNFRSF17
  • tumor necrosis factor receptor superfamily, member 17


BCMA, B cell maturation, is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development, function and regulation. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity.

  1. Madry, C. et al. (1998) Int. Immunol. 10:1693.
  2. Gras, M. et al. (1995) Int. Immunol. 7:1093.
  3. Kwon, B. et al. (1999) Curr. Opin. Immunol. 11:340.
  4. Marsters, S. et al. (2000) Curr. Biol. 10:785.
  5. Thompson, J. et al. (2000) J. Exp. Med. 192:129.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for BCMA/TNFRSF17 Antibody (FAB193P)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.

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Showing Publications 1 - 5 of 5.
Publications using FAB193P Applications Species
M Chapellier, P Peña-Martí, R Ramakrishn, M Eriksson, M Safaee-Tal, C Orsmark-Pi, H Lilljebjör, C Högberg, A Hagström-A, T Fioretos, J Larsson, M Järås Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells Haematologica, 2019;0(0):. 2019 [PMID: 30819903] (Flow Cytometry, Human) Flow Cytometry Human
AL Garfall, EA Stadtmauer, WT Hwang, SF Lacey, JJ Melenhorst, M Krevvata, MP Carroll, WH Matsui, Q Wang, MV Dhodapkar, K Dhodapkar, R Das, DT Vogl, BM Weiss, AD Cohen, PA Mangan, EC Ayers, S Nunez-Cruz, I Kulikovska, MM Davis, A Lamontagne, K Dengel, ND Kerr, RM Young, DL Siegel, BL Levine, MC Milone, MV Maus, CH June Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma JCI Insight, 2018;3(8):. 2018 [PMID: 29669947] (Flow Cytometry, Human) Flow Cytometry Human
R de la Varg, B Rodríguez-, GA Añez, F Medina Var, JJ Pérez Vene, JA Brieva, C Rodríguez Clinical relevance of circulating anti-ENA and anti-dsDNA secreting cells from SLE patients and their dependence on STAT-3 activation Eur. J. Immunol., 2017;0(0):. 2017 [PMID: 28463395] (Flow Cytometry, Human) Flow Cytometry Human
Frigyesi I, Adolfsson J, Ali M, Christophersen M, Johnsson E, Turesson I, Gullberg U, Hansson M, Nilsson B Robust isolation of malignant plasma cells in multiple myeloma. Blood, 2014;123(9):1336-40. 2014 [PMID: 24385542] (Flow Cytometry, Human) Flow Cytometry Human
Hardenberg G, Fernandez L, Hendriks J, Chebli K, Jacquet C, Sitbon M, Hahne M, Medema JP APRIL facilitates viral-induced erythroleukemia but is dispensable for T cell immunity and lymphomagenesis. J. Leukoc. Biol., 2008;84(2):380-8. 2008 [PMID: 18483203] (Flow Cytometry, Mouse) Flow Cytometry Mouse

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Gene Symbol TNFRSF17