Immunohistochemistry-Paraffin: BCL11B Antibody [NB100-2600] - Section of human skin tumor (higher magnification). Antibody: Affinity purified rabbit anti-Bcl11b used at a dilution of 1:500. Detection: DAB staining using ...read more
Immunohistochemistry-Paraffin: BCL11B Antibody [NB100-2600] - P7 brain mouse section was stained with anti-BCL11B antibody. Image from verified customer review.
Immunohistochemistry: BCL11B Antibody [NB100-2600] - Immunohistochemistry and FISH of AML cases. Immunohistochemistry analysis of BCL11B-expressing AML samples #59810, #57863 and #13 carrying t(2;14)(q22.3;q32.3), ...read more
Immunohistochemistry-Paraffin: BCL11B Antibody [NB100-2600] - Section of human skin tumor. Antibody: Affinity purified rabbit anti-Bcl11b used at a dilution of 1:500. Detection: DAB staining using anti-Rabbit IHC ...read more
The immunogen recognized by this antibody maps to a region between residue 850 and the C-terminus (residue 894) of human B-cell CLL/lymphoma 11B using the numbering given in Swiss-Prot entry Q9C0K0 (GeneID 64919).
Epitope exposure is recommended to enhance staining. ICC/IF reactivity reported in scientific literature (PMID: 24155294). IHC-F reactivity reported in scientific literature (PMID: 24155294). BCL11B antibody validated for IHC-P from a verified customer review.
Read 1 Review rated 5 using NB100-2600 in the following applications:
Rat reactivity reported in scientific literature (PMID: 26465886). Mouse reactivity reported from a verified customer review. Orangutan, Gorilla, Chimpanzee, X.tropicalis (100%).
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
TBS and 0.1% BSA
0.09% Sodium Azide
Immunogen affinity purified
Alternate Names for BCL11B Antibody
B-cell CLL/lymphoma 11B (zinc finger protein)
B-cell CLL/lymphoma 11B
B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein
B-cell lymphoma/leukaemia 11B
B-cell lymphoma/leukemia 11B
COUP-TF-interacting protein 2
Radiation-induced tumor suppressor gene 1 protein
zinc finger protein hRit1 alpha
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in placental, cardiac, hepatic and embryonic development. NCOA6 is over-expressed in several breast cancer cell lines.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.