BCL11B Antibody

Images

 
Immunohistochemistry: BCL11B Antibody [NB100-2600] - Sample: FFPE section of human skin tumor. Antibody: Affinity purified rabbit anti-Bcl11b used at a dilution of 1:500. Detection: DAB staining using anti-Rabbit IHC ...read more
Immunohistochemistry-Paraffin: BCL11B Antibody [NB100-2600] - P7 brain mouse section was stained with anti-BCL11B antibody. Image from verified customer review.
Immunohistochemistry: BCL11B Antibody [NB100-2600] - Sample: FFPE section of human skin tumor (higher magnification). Antibody: Affinity purified rabbit anti-Bcl11b used at a dilution of 1:500. Detection: DAB staining ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

BCL11B Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 850 and the C-terminus (residue 894) of human B-cell CLL/lymphoma 11B using the numbering given in Swiss-Prot entry Q9C0K0 (GeneID 64919).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BCL11B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:100-1:500
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 1:100-1:500
Application Notes
Epitope exposure is recommended to enhance staining. ICC/IF reactivity reported in scientific literature (PMID: 24155294). IHC-F reactivity reported in scientific literature (PMID: 24155294).
Reviewed Applications
Read 1 Review rated 5
using
NB100-2600 in the following applications:

Publications
Read Publications using
NB100-2600 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for BCL11B Antibody

  • B-cell CLL/lymphoma 11B (zinc finger protein)
  • B-cell CLL/lymphoma 11B
  • B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein
  • B-cell lymphoma/leukaemia 11B
  • B-cell lymphoma/leukemia 11B
  • BCL-11B
  • BCL11B/TRDC fusion
  • COUP-TF-interacting protein 2
  • CTIP-2
  • CTIP2ZNF856B
  • hRit1
  • hRIT1-alpha
  • Radiation-induced tumor suppressor gene 1 protein
  • RIT1
  • zinc finger protein hRit1 alpha

Background

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in placental, cardiac, hepatic and embryonic development. NCOA6 is over-expressed in several breast cancer cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for BCL11B Antibody (NB100-2600)(3)

Review for BCL11B Antibody (NB100-2600) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.
We have 1 review tested in 1 application: IHC-P.

Reviews using NB100-2600:
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IHC-P
(1)
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Mouse
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Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin BCL11B NB100-2600
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reviewed by:
Anonymous
IHC-P Mouse 10/03/2014
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Summary

ApplicationImmunohistochemistry-Paraffin
Sample Testedmouse brain
SpeciesMouse

Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Recent Reviews

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Anonymous
10/03/2014
Application: IHC-P
Species: Mouse

Bioinformatics

Gene Symbol BCL11B
Entrez
Uniprot