B7-H2/ICOSLG Antibody (2D3) Summary
A recombinant full-length human ICOSLG/ICOSL. Human B7H2-mIg fusion protein.
Immunogen affinity purified
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Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.2)
0.09% Sodium Azide
Immunogen affinity purified
- Flow Cytometry 0.5 ug/million cells
- Immunohistochemistry-Paraffin 1:50
Alternate Names for B7-H2/ICOSLG Antibody (2D3)
- B7H2B7 homolog 2
- B7-H2B7-related protein 1
- B7RP1B7-like protein Gl50
- CD275 antigen
- GL50transmembrane protein B7-H2 ICOS ligand
- inducible T-cell co-stimulator ligand
- KIAA0653ICOS ligand
B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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