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B7-H2/ICOSLG Products

Antibodies
B7-H2/ICOSLG Antibody (136726 ...
B7-H2/ICOSLG Antibody (136726) [Un...
MAB165
MAB0041, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0102B)." class="big_lightbox" target="_blank"> Flow Cytometry B7-H2/ICOSLG Antibody (136726) [Unconjugated]
MAB100), Recombinant Human B7-H2 Fc Chimera (Catalog # 165-B7) stimulates proliferation in PHA-activated human T cells in a dose-dependent manner (orange line). Under these conditions, proliferation elicited by Recombinant Human B7-H2 Fc Chimera (3 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human B7-H2 Monoclonal Antibody (Catalog # MAB165). The ND50 is typically 1-4 µg/mL." class="big_lightbox" target="_blank"> Neutralization B7-H2/ICOSLG Antibody (136726) [Unconjugated]
Species: Hu
Applications: Flow, B/N, CyTOF-ready
Host: Mouse Monoclonal
B7-H2/ICOSLG Antibody [Unconj ...
B7-H2/ICOSLG Antibody [Unconjugated]
AF165
HAF017). A specific band was detected for B7-H2 at approximately 75 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot B7-H2/ICOSLG Antibody [Unconjugated]
AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107)." class="big_lightbox" target="_blank"> Flow Cytometry B7-H2/ICOSLG Antibody [Unconjugated]
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
B7-H2/ICOSLG Antibody (599841 ...
B7-H2/ICOSLG Antibody (599841) [Un...
MAB158
MAB005, open histogram), followed by Phycoerythrin-conjugated Anti-Rat IgG F(ab')2Secondary Antibody (Catalog # F0105B)." class="big_lightbox" target="_blank"> Flow Cytometry B7-H2/ICOSLG Antibody (599841) [Unconjugated]
NL013) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces. View our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="big_lightbox" target="_blank"> Immunocytochemistry B7-H2/ICOSLG Antibody (599841) [Unconjugated]
Species: Mu
Applications: Flow, CyTOF-ready, ICC/IF
Host: Rat Monoclonal
Antibody Pairs
B7-H2/ICOSLG Antibody Pair [H ...
B7-H2/ICOSLG Antibody Pair [HRP]
NBP2-79653
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Human B7-H2 DuoSet ELISA, 5 P ...
Human B7-H2 DuoSet ELISA, 5 Plate
DY165-05
Species: Hu
Applications: ELISA
Mouse B7-H2 DuoSet ELISA, 5 P ...
Mouse B7-H2 DuoSet ELISA, 5 Plate
DY10083-05
Species: Mu
Applications: ELISA
Human B7-H2/ICOSLG ELISA Kit ...
Human B7-H2/ICOSLG ELISA Kit (Colo...
NBP3-43462
Species: Hu
Lysates
B7-H2/ICOSLG Overexpression L ...
B7-H2/ICOSLG Overexpression Lysate
NBP2-04349
Species: Hu
Applications: WB
Proteins
Recombinant Human B7-H2 Fc Ch ...
Recombinant Human B7-H2 Fc Chimera...
165-B7
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human B7-H2 His-t ...
Recombinant Human B7-H2 His-tag Pr...
8206-B7
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human B7-H2 Fc Ch ...
Recombinant Human B7-H2 Fc Chimera...
AVI165
169-CS) is immobilized at 0.5 μg/mL (100 μL/well), Biotinylated Recombinant Human B7-H2 Fc Chimera Avi-tag (AVI165) that produces a 50% optimal binding response is found to be 1-6 ng/mL." class="big_lightbox" target="_blank"> Binding Activity B7-H2/ICOSLG [Biotin]
AVI165) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 80-100 kDa and 160-200 kDa, respectively." class="big_lightbox" target="_blank"> N/A B7-H2/ICOSLG [Biotin]
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  

Description

B7-RP1 is a 40 kD protein, also known as ICOS ligand, B7-H2, and B7h. It has recently been clustered as CD275. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells and macrophages. The expression of this antigen is increased by TNF- alpha stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 23308
Alternate Names
  • B7H2B7 homolog 2
  • B7-H2B7-related protein 1
  • B7RP1B7-like protein Gl50
  • B7RP-1LICOS
  • CD275 antigen
  • CD275
  • GL50transmembrane protein B7-H2 ICOS ligand
  • ICOSL
  • ICOS-L
  • inducible T-cell co-stimulator ligand
  • KIAA0653ICOS ligand

Research Areas for B7-H2/ICOSLG

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication