ATP7A Antibody

Product Discontinued

ATP7A Antibody Summary

• Immunogen: Peptide with sequence C-HKNNWNIEDNNIKN corresponding to internal region according to NP_000043.3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ATP7A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
• Application Notes: WB: Preliminary experiments gave an approx. 55 kDa band in human colon lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 163 kDa band according to NP_000043.3. The 55 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for ATP7A Antibody

• ATPase, Cu++ transporting, alpha polypeptide
• Copper pump 1
• copper-transporting ATPase 1
• Cu++-transporting P-type ATPase
• DSMAX
• EC 3.6.3
• EC 3.6.3.4
• MC1
• Menkes disease-associated protein
• Menkes syndrome
• MK
• MNKFLJ17790
• OHS
• SMAX3

Background

ATP7A - ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ATP7A Antibody (NBP1-20892)(1)

Publication using NBP1-20892

• Schlief ML, West T, Craig AM et al. Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Proc Natl Acad Sci U S A 2006-10-03 [PMID: 17003121]

Bioinformatics

• Gene Symbol: ATP7A
• Entrez:
  • 538(Human)
• Uniprot:
  • Q04656(Human)