ATG5 Antibody (603813) [Alexa Fluor™ Plus 555]

• Reactivity: Hu, Mu, Rt
• Clone: 603813
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

ATG5 Antibody (603813) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human, mouse, and rat ATG5 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ATG5 Antibody (603813) [Alexa Fluor™ Plus 555]

• APG5 (Autophagy 5, S. Cerevisiae)-Like
• APG5 autophagy 5-like (S. cerevisiae)
• APG5
• APG5L
• APG5-LIKE
• ASP
• ASPAPG5-LIKE
• ATG5 autophagy related 5 homolog (S. cerevisiae)
• ATG5 Autophagy Related 5 Homolog
• ATG5
• Autophagy protein 5
• Autophagy Related 5
• HAPG5
• SCAR25

Background

ATG5 (Autophagy-related Protein), also known as APG5L and Apoptosis-specific Protein, is a ubiquitous 32 kDa member of the ATG family of proteins. ATG5 exists as a covalent heterodimer with ATG12 through the creation of a Lys-Gly linkage. The ATG5:ATG12 heterodimer associates noncovalently with an ATG16 multimer to generate autophagosomes. Human ATG5 is 275 amino acids in length and contains N- and C-terminal ubiquitin-like domains (aa 15‑105 and 187‑275) separated by a helix-rich linker region that contains a dimerizing Lys at position 130. There are two potential alternate start sites at Met80 and Met173. Over aa 99‑193, human ATG5 is 97% aa identical to mouse ATG5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.