ATG5 Products

ATG5 Antibody
ATG5 Antibody
Species: Hu, Mu, Rt, Po, Bv, Pm, Xp, Ze
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP, PLA
Host: Rabbit Polyclonal
ATG5 Antibody
ATG5 Antibody
Species: Hu, Mu, Rt, Po, Bv, Chicken
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ATG5 Antibody (603813) [Uncon ...
ATG5 Antibody (603813) [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Host: Mouse Monoclonal
ATG5 Overexpression Lysate (N ...
ATG5 Overexpression Lysate (Native)
Applications: WB
ATG5 Peptide
ATG5 Peptide
Species: Hu
ATG5 Recombinant Protein
ATG5 Recombinant Protein
Species: Hu
Applications: WB, ELISA, PA
ATG5 Partial Recombinant Prot ...
ATG5 Partial Recombinant Protein
Species: Hu
Applications: WB, ELISA, PA
Species: Hu


ATG5 is required for autophagy, an important mechanism for nonselective intracellular breakdown whereby cytosol and organelles are encapsulated in vesicles, which are then engulfed and digested by lytic vacuoles/lysosomes. ATG5 conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation of ATG5 to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. ATG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.


Entrez Human
Uniprot Human
Product By Gene ID 9474
Alternate Names
  • Autophagy protein 5
  • APG5LS. cerevisiae)-like
  • APG5 autophagy 5-like (S. cerevisiae)
  • ATG5 autophagy related 5 homolog (S. cerevisiae)

Research Areas for ATG5

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Ubiquitin Proteasome Pathway

Bioinformatics Tool for ATG5

Discover related pathways, diseases and genes to ATG5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related ATG5 Blog Posts

Check out the latest blog posts on ATG5.
WIPI1 - An essential regulator of early autophagosome assembly
WD repeat domain phosphoinositide-interacting protein 1 (WIPI) is involved in the lysosomal degradation of cytoplasmic components during starvation-induced autophagy. WIPI1 is a seven bladed beta-propeller protein that provides a scaffold for the ...    Read more.
ATG4C - A regulator of the early steps of autophagosome assembly
Autophagy is an important cellular process that maintains homeostasis by degrading and recycling damaged proteins and organelles. Autophagy receptors, such as p62/SQSTM1, recognize these intracellular cargo and mediate their engulfment by the doubl...    Read more.
ATG16L2 - An autophagy-related protein with unknown functions
Autophagy is a process by which cells degrade and recycle damaged organelles or misfolded proteins. These various cargo are engulfed in a double-membrane structure called the autophagosome. The autophagosome then fuses with the lysosome to facilit...    Read more.
ATG4D - A regulator of autophagy and apoptosis
Autophagy is an essential cellular process whereby damaged proteins and organelles are degraded and recycled. Autophagy, while happening constantly at a basal level, is tightly regulated and can be further induced under cellular stress. One of the...    Read more.
ATG4B - a cysteine protease involved in autophagosome elongation
Autophagy can be broken down into 4 main stages: phagophore nucleation, autophagosome elongation, autophagosome docking and fusion with a lysosome, and vesicle breakdown and degradation. ATG4B is one of four ATG4 homologs (ATG4A, ATG4B, ATG4C, and...    Read more.
ATG16L1 - a key player in the development of the autophagosome
Untitled DocumentLike apoptosis, autophagy is a highly regulated physiologic process that involves cellular degradation and recycling of organelles and macromolecules. Autophagy is a survival mechanism induced by states of stress, s...    Read more.
ATG5 - an essential regulator of autophagosome assembly
Autophagy is important for the removal of damaged organelles or proteins as well as for the regulation of cellular homeostasis in response to stress. Proteins or organelles that are targeted for degradation are engulfed in a double-membrane structu...    Read more.
ATG7 - an E1 enzyme for the ubiquitin-like autophagy proteins
Autophagy is an essential cellular process that maintains homeostasis through the degradation and recycling of cytoplasmic organelles and macromolecules. Substrates targeted for autophagy are engulfed in a double-membrane structure called the auto...    Read more.
p62/SQSTM1 - targeting ubiquitinated proteins for autophagic degradation
During autophagy ubiquitinated cargo or substrates are engulfed in a double-membrane autophagosome and transported to the lysosome for degradation. This process is important for maintaining cellular homeostasis and for degrading damaged organelles...    Read more.
ATG12 - a ubiquitin-like protein essential for autophagosome assembly
Atg12 is a ubiquitin-like protein that plays an essential role in cellular homeostasis by regulating the degradation and recycling of cytoplasmic organelles and macromolecules. Atg12 is one of two ubiquitin-like protein systems that is required du...    Read more.
LC3/LC3B - measuring autophagosome formation and autophagic flux
Microtubule-associated protein-1 light chain 3 (LC3/LC3B) is a ubiquitin-like protein involved in the formation of the autophagosome. It is homologous to the yeast Atg8 protein. Autophagosomes are important for the degradation and recycling of intr...    Read more.
ATG9A - early marker autophagosome assembly
ATG9A is the only essential integral membrane protein involved in autophagy. ATG9A contains six transmembrane domains and initiates the assembly of autophagosomes. The autophagosome is a double-membrane structure that engulfs and eventually degrade...    Read more.
Comprehensive Autophagy Research Tools - New Catalog Available Now!
Autophagy, a protein degradation process through autophagosome-lysosomal pathway, is important for cellular homeostasis and plays a role in many diseases. To help researchers learn more about this process and the products available for its study, N...    Read more.
Essential to Death: ATG5 (autophagy protein 5, apoptosis-specific protein ASP)
The ATG5 protein belongs to the ATG autophagy regulator family. This family controls the highly conserved cell's homeostatic response to a wide variety of both self- and foreign-originating cellular stimuli. ATG5 itself is ubiquitously expressed in mo...    Read more.
ATG5: Roles in Cellular Defense
ATG5, or Autophagy Related 5, is a protein crucial for autophagy. Autophagy is a mechanism in which dysfunctional or pathogenic cells or cellular components are degraded and sometimes recycled. This process happens when ATG5 conjugates with another pr...    Read more.
ATG5, Autophagy and Apoptosis
ATG5 is a member of the ATG family that regulates autophagy, the evolutionary conserved homeostatic response to a diverse variety of self- and foreign-originating cellular stresses. ATG5 is ubiquitously expressed in cells and found co-localized with c...    Read more.
ATG5: From Autophagy to Alzheimer's Disease
Autophagy is a conserved mechanism whereby cells form double membrane autophagosomes to sequester cytoplasmic components for subsequent destruction by fusion with lysosomes (eukaryotes) or vacuoles (yeast). Targets of autophagy include aging proteins,...    Read more.
The Role of LC3 within the Autophagic Pathway
We at Novus Biologicals have a broad antibody databasecovering the area of autophagy - over 1400 reagents in total. Autophagy is bulk degradation of cytoplasmic components - literally, self-digestion of the cell. Double-membrane vesicles, called autop...    Read more.
Read more ATG5 related blogs.