ATG4C Antibody (24GB6165)

• Reactivity: Hu
• Applications: WB, Flow, Mycoplasma
• Clone: 24GB6165
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

ATG4C Antibody (24GB6165) Summary

• Immunogen: Recombinant protein of human ATG4C (Uniprot: Q96DT6)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ATG4C
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ATG4C Antibody (24GB6165)

• APG4 autophagy 4 homolog C (S. cerevisiae)
• APG4 autophagy 4 homolog C
• APG4C
• ATG4 autophagy related 4 homolog C (S. cerevisiae)
• AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteineendopeptidase (S. cerevisiae)
• AUTL1
• AUTL3APG4-C
• AUT-like 1, cysteine endopeptidase
• AUT-like 3 cysteine endopeptidase
• autophagin-3
• Autophagy-related cysteine endopeptidase 3
• Autophagy-related protein 4 homolog C
• cysteine protease ATG4C
• EC 3.4.22
• EC 3.4.22.-
• FLJ14867

Background

ATG4C is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATG4C