ATG4C Products

Description

ATG4C is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Bioinformatics

Product By Gene ID

84938

Alternate Names

APG4 autophagy 4 homolog C (S. cerevisiae) APG4 autophagy 4 homolog C APG4C ATG4 autophagy related 4 homolog C (S. cerevisiae) AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteineendopeptidase (S. cerevisiae) AUTL1 AUTL3APG4-C AUT-like 1, cysteine endopeptidase AUT-like 3 cysteine endopeptidase autophagin-3 Autophagy-related cysteine endopeptidase 3 Autophagy-related protein 4 homolog C cysteine protease ATG4C EC 3.4.22 EC 3.4.22.- FLJ14867

Research Areas for ATG4C

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer

Related ATG4C Blog Posts

Check out the latest blog posts on ATG4C.

ATG4C - A regulator of the early steps of autophagosome assembly Autophagy is an important cellular process that maintains homeostasis by degrading and recycling damaged proteins and organelles. Autophagy receptors, such as p62/SQSTM1, recognize these intracellular cargo and mediate their engulfment by the doubl...    Read more.

Read more ATG4C related blogs.