ASC/TMS1 Antibody [Janelia Fluor® 646]


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Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Janelia Fluor 646

ASC/TMS1 Antibody [Janelia Fluor® 646] Summary

A synthetic peptide made to an N-terminal portion of the human ASC/TMS1 protein (between residues 1-50) [Uniprot: Q9ULZ3]
Cytoplasm. Note: Upstream of caspase activation, a redistribution from the cytoplasm to the aggregates occurs. These appear as hollow, perinuclear spherical, ball-like structures.
Immunogen affinity purified
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  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reactivity with Rat reported in PMID 24464748

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ASC/TMS1 Antibody [Janelia Fluor® 646]

  • apoptosis-associated speck-like protein containing a CARD
  • ASC
  • CARD5
  • caspase recruitment domain protein 5
  • Caspase recruitment domain-containing protein 5
  • hASC
  • PYD and CARD domain-containing protein
  • Target of methylation-induced silencing 1
  • TMS
  • TMS1
  • TMS-1


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ASC/TMS1 Antibody (NBP1-78977JF646) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-78977AF350
Alexa Fluor 405 NBP1-78977AF405
Alexa Fluor 488 NBP1-78977AF488
Alexa Fluor 532 NBP1-78977AF532
Alexa Fluor 594 NBP1-78977AF594
Alexa Fluor 647 NBP1-78977AF647
Alexa Fluor 700 NBP1-78977AF700
Alexa Fluor 750 NBP1-78977AF750
Biotin NBP1-78977B
DyLight 350 NBP1-78977UV
DyLight 405 NBP1-78977V
DyLight 488 NBP1-78977G
DyLight 550 NBP1-78977R
DyLight 594 NBP1-78977DL594
DyLight 650 NBP1-78977C
DyLight 680 NBP1-78977FR
DyLight 755 NBP1-78977IR
FITC NBP1-78977F
HRP NBP1-78977H
Janelia Fluor 549 NBP1-78977JF549
Janelia Fluor 646 NBP1-78977JF646

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Bioinformatics Tool for ASC/TMS1 Antibody (NBP1-78977JF646)

Discover related pathways, diseases and genes to ASC/TMS1 Antibody (NBP1-78977JF646). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for ASC/TMS1 Antibody (NBP1-78977JF646)

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Blogs on ASC/TMS1.

The inflammasome: an inflammation-initiating machine, Novus Biologicals
By Stephanie Melchor The inflammasome is a large, multimeric protein complex found primarily in innate immune cells, which are white blood cells that can attack a wide range of pathogenic threats. Three main elements...  Read full blog post.

Immunity’s flipside: Microglia promote Alzheimer’s pathology during inflammation
By Jamshed Arslan Pharm.D. Microglia are brain's macrophages. In Alzheimer's disease (AD), microglia clear up protein aggregates called amyloid beta plaques. The connection between immune activation and AD is unclea...  Read full blog post.

CARD & NFKB Antibodies for Apoptosis Research
Apoptosis is one of the main types of programmed cell death which involves a cascade of biochemical events leading to specific cell morphology characteristics and ultimately death of cells.Caspases play crucial roles in modulating cellular signaling...  Read full blog post.

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Contact Information

Learn the difference between western blot and simple western

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Gene Symbol PYCARD