ASC/TMS1 Products

Antibodies
Lysates
ASC/TMS1 Overexpression Lysat ...
ASC/TMS1 Overexpression Lysate (De...
H00029108-T01
Species: Hu
Applications: WB
ASC/TMS1 Overexpression Lysat ...
ASC/TMS1 Overexpression Lysate (Na...
NBL1-15017
Applications: WB
ASC/TMS1 Overexpression Lysat ...
ASC/TMS1 Overexpression Lysate (Na...
NBL1-15016
Applications: WB
Proteins
ASC/TMS1 Recombinant Protein
ASC/TMS1 Recombinant Protein
H00029108-P01
Species: Hu
Applications: WB, ELISA, Func, PA
ASC/TMS1 Recombinant Protein ...
ASC/TMS1 Recombinant Protein Antigen
NBP2-48925PEP
Species: Hu
Applications: AC
ASC/TMS1 Recombinant Protein ...
ASC/TMS1 Recombinant Protein Antigen
NBP2-49133PEP
Species: Hu
Applications: AC
RNAi
ASC/TMS1 RNAi
ASC/TMS1 RNAi
H00029108-R01
Species: Hu
ASC/TMS1 RNAi
ASC/TMS1 RNAi
H00029108-R02
Species: Hu

Description

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells. Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 29108
Alternate Names
  • Target of methylation-induced silencing 1
  • hASC
  • Caspase recruitment domain-containing protein 5
  • caspase recruitment domain protein 5
  • TMS-1
  • TMS1apoptosis-associated speck-like protein containing a CARD
  • CARD5TMS
  • ASCMGC10332
  • PYD and CARD domain-containing protein
  • PYD and CARD domain containing

Research Areas for ASC/TMS1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Biology

PTMs for ASC/TMS1

Learn more about PTMs related to ASC/TMS1.

Methylation
Cleavage
Demethylation
Phosphorylation
Acetylation
Deacetylation
Reduction
Acylation

Bioinformatics Tool for ASC/TMS1

Discover related pathways, diseases and genes to ASC/TMS1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related ASC/TMS1 Blog Posts

Check out the latest blog posts on ASC/TMS1.
CARD & NFKB Antibodies for Apoptosis Research
Apoptosis is one of the main types of programmed cell death which involves a cascade of biochemical events leading to specific cell morphology characteristics and ultimately death of cells.Caspases play crucial roles in modulating cellular signaling...    Read more.
Read more ASC/TMS1 related blogs.