Arylsulfatase G/ARSG Antibody [Allophycocyanin]

• Reactivity: Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Allophycocyanin

Arylsulfatase G/ARSG Antibody [Allophycocyanin] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse Arylsulfatase G/ARSG
  Gly17-Val525
  Accession # Q3TYD4
• Specificity: Detects mouse Arylsulfatase G/ARSG in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant mouse ARSA, recombinant human (rh) ARSB and rhARSJ is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: ARSG
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Arylsulfatase G/ARSG Antibody [Allophycocyanin]

• ARSG
• Arylsulfatase G
• ASG
• EC 3.1.6
• EC 3.1.6.-
• EC 3.1.6.4
• KIAA1001ASG

Background

Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate. The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum as typically seen for lysosomal sulfatases. The protein accumulates within lysosomes and is also a glycoprotein that binds specifically to mannose 6-phosphate receptors. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARSG