Arginase 1/ARG1/liver Arginase Antibody (ARG1/1126) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC-P
Clone
ARG1/1126
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Arginase 1/ARG1/liver Arginase Antibody (ARG1/1126) [DyLight 405] Summary

Immunogen
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein
Localization
Cytoplasmic
Marker
Hepatocellular Carcinoma Marker
Specificity
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Isotype
IgG3 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ARG1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody shomld be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Arginase 1/ARG1/liver Arginase Antibody (ARG1/1126) [DyLight 405]

  • AI
  • ARG1
  • Arginase 1
  • arginase, liver
  • Arginase-1
  • EC 3.5.3.1
  • Liver Arginase
  • Liver-type arginase
  • PGIF
  • Type I Arginase

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ARG1