ARAP1 Antibody [DyLight 488]

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 488

ARAP1 Antibody [DyLight 488] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1160 and 1210 of human centaurin, delta 2 (ankyrin repeat, and pleckstrin homology domains-containing protein 1) using the numbering given in entry NP_056057.1 (GeneID 116985).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARAP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in (PMID: 22573888).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ARAP1 Antibody [DyLight 488]

• arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
• ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
• centaurin, delta 2
• Centaurin-delta-2
• CENTD2ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containingprotein 1
• cnt-d2
• KIAA0782centaurin-delta-2

Background

ARAP1 is encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. The RHO-GAP activity may mediate cell rounding and loss of stress fibers. At least three transcript variants encoding different isoforms have been found for this gene, but the full-length natures of all variants have not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARAP1