Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
ARAP1 is encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. The RHO-GAP activity may mediate cell rounding and loss of stress fibers. At least three transcript variants encoding different isoforms have been found for this gene, but the full-length natures of all variants have not been determined.
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human Human |
Product By Gene ID |
116985 |
Alternate Names |
- arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
- centaurin, delta 2
- Centaurin-delta-2
- CENTD2ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containingprotein 1
- Cnt-d2
- cnt-d2
- KIAA0782centaurin-delta-2
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Research Areas for ARAP1
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication