ARAP1 Products

Description

ARAP1 is encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. The RHO-GAP activity may mediate cell rounding and loss of stress fibers. At least three transcript variants encoding different isoforms have been found for this gene, but the full-length natures of all variants have not been determined.

Bioinformatics

Entrez	116985 Human 69710 Mouse
Uniprot	AAH56401 Human NP_056057 Human Q96P48 Human
Product By Gene ID	116985
Alternate Names	Cnt-d2 Centaurin-delta-2 cnt-d2 centaurin, delta 2 KIAA0782centaurin-delta-2 CENTD2ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containingprotein 1 arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

Diseases related to ARAP1

Discover more about diseases related to ARAP1.

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Insulin Resistance
Malignant Neoplasms
Hypertensive Disease
Leukemia
Coronary Heart Disease
Stenosis
Malignant Neoplasm Of Breast
Coronary Artery Disease
Sarcoma
Carcinoma
Fibrosis
Cardiovascular Diseases
Neoplasms
Nervousness
Mammary Neoplasms
L1 Acute Lymphoblastic Leukemia
Stricture Of Artery

Pathways for ARAP1

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Localization
Cell Growth
Glucose Homeostasis
Transport
Drug Resistance
Reverse Transcription
Insulin Processing
Endocytosis
Receptor Recycling
Pathogenesis
Regulation Of Blood Pressure

Research Areas for ARAP1

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Cell Cycle and Replication

PTMs for ARAP1

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Phosphorylation
Ribosylation
Ubiquitination

Bioinformatics Tool for ARAP1

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