Apelin Antibody Pair

Product Discontinued

Apelin Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00008862-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human APLN.
  
  
• Capture antibody: mouse monoclonal anti-APLN IgG1 Kappa (100 ug)
• Detection antibody: biotinylated mouse monoclonal anti-APLN IgG1 Kappa (50 ug)
• Standard Curve Range: 10 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: APLN
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 10 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Apelin Antibody Pair

• AGTRL1 ligand
• AGTRL1 Lligand
• APEL
• Apelin
• apelin, AGTRL1 ligand
• APJ endogenous ligand
• APLN
• XNPEP2

Background

Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei and is an endogenous ligand for APJ, a G protein-coupled orphan receptor which is an alternative coreceptor with CD4 for HIV-1. Apelin and APJ are ubiquitously expressed in peripheral tissues, with highest levels reported for heart and lungs, as well several regions within the central nervous system. The actions of apelin remain largely unknown: Apelin inhibits HIV-1 entry in cells coexpressing CD4 and APJ; the oral intake of Apelin in colostrum and breast milk could have a role in the modulation of the immune responses in neonates; more recent studies have also indicated a role for Apelin in the central control of body fluid homeostasis, by influencing AVP release and drinking behavior. In the cardiovascular system several actions of Apelin have been described, including endothelium-dependent vasodilatation, vasoconstriction through direct action on smooth muscle and positive inotropism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: APLN