alpha Desmuslin Antibody (OTI7H6) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: OTI7H6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

alpha Desmuslin Antibody (OTI7H6) [Janelia Fluor® 669] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 329-580 of human SYNM(NP_663780) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SYNM
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for alpha Desmuslin Antibody (OTI7H6) [Janelia Fluor® 669]

• desmuslin
• DMNEC 1.4.99.1
• EC 2.6.1.16
• KIAA0353synemin beta
• SYNDesmuslin
• synemin alpha
• synemin
• synemin, intermediate filament protein

Background

alpha Desmuslin is encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SYNM