AKR1C2 Antibody (CPTC-AKR1C2-1) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
CPTC-AKR1C2-1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

AKR1C2 Antibody (CPTC-AKR1C2-1) [DyLight 350] Summary

Immunogen
Recombinant human full-length AKR1C2 protein (Uniprot: P52895)
Localization
Cytoplasm
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
AKR1C2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AKR1C2 Antibody (CPTC-AKR1C2-1) [DyLight 350]

  • aldo-keto reductase family 1 member C2
  • aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acidbinding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
  • BABP
  • Chlordecone reductase homolog HAKRD
  • DD
  • DD-2
  • DD2DD/BABP
  • DDH2FLJ53800
  • Dihydrodiol dehydrogenase 2
  • Dihydrodiol dehydrogenase/bile acid-binding protein
  • EC 1.1.1,3-alpha-HSD3
  • EC 1.1.1.213
  • EC 1.3.1.20
  • HAKRDAKR1C-pseudo
  • HBAB
  • MCDR2
  • pseudo-chlordecone reductase
  • Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
  • type II dihydrodiol dehydrogenase
  • Type III 3-alpha-hydroxysteroid dehydrogenase

Background

AKR1C2 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol AKR1C2