AKR1C2 Antibody (CPTC-AKR1C2-1) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Applications: WB, IHC, MA
• Clone: CPTC-AKR1C2-1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

AKR1C2 Antibody (CPTC-AKR1C2-1) [Alexa Fluor™ Plus 647] Summary

• Immunogen: Recombinant human full-length AKR1C2 protein (Uniprot: P52895)
• Localization: Cytoplasm
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: AKR1C2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for AKR1C2 Antibody (CPTC-AKR1C2-1) [Alexa Fluor™ Plus 647]

• aldo-keto reductase family 1 member C2
• aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acidbinding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
• BABP
• Chlordecone reductase homolog HAKRD
• DD
• DD-2
• DD2DD/BABP
• DDH2FLJ53800
• Dihydrodiol dehydrogenase 2
• Dihydrodiol dehydrogenase/bile acid-binding protein
• EC 1.1.1,3-alpha-HSD3
• EC 1.1.1.213
• EC 1.3.1.20
• HAKRDAKR1C-pseudo
• HBAB
• MCDR2
• pseudo-chlordecone reductase
• Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
• type II dihydrodiol dehydrogenase
• Type III 3-alpha-hydroxysteroid dehydrogenase

Background

AKR1C2 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AKR1C2