AKR1C2 Products

Description

AKR1C2 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Bioinformatics

Entrez	1646 Human
Uniprot	AAH07024 Human AAH07024.1 Human AAH63574 Human NM_001354 Human NP_995317 Human P52895 Human
Product By Gene ID	1646
Alternate Names	aldo-keto reductase family 1 member C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acidbinding protein; 3-alpha hydroxysteroid dehydrogenase, type III) BABP Chlordecone reductase homolog HAKRD DD DD-2 DD2DD/BABP DDH2FLJ53800 Dihydrodiol dehydrogenase 2 Dihydrodiol dehydrogenase/bile acid-binding protein EC 1.1.1,3-alpha-HSD3 EC 1.1.1.213 EC 1.3.1.20 HAKRDAKR1C-pseudo HBAB MCDR2 pseudo-chlordecone reductase Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase type II dihydrodiol dehydrogenase Type III 3-alpha-hydroxysteroid dehydrogenase