AIBZIP Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: AIBZIP Antibody [NBP1-90205] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, nuclear membrane & mitochondria.

Analysis in human prostate and pancreas tissues using Anti-CREB3L4 antibody. Corresponding CREB3L4 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: AIBZIP Antibody [NBP1-90205] - Staining of human prostate shows high expression.

Immunohistochemistry-Paraffin: AIBZIP Antibody [NBP1-90205] - Staining of human pancreas shows low expression as expected.

• Reactivity: Hu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

AIBZIP Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit AIBZIP Antibody - BSA Free (NBP1-90205) is a polyclonal antibody validated for use in IHC and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: ELERHNISLVAQLRQLQTLIAQTSNKAAQTSTCVLILLFSLALIILPSFSPFQSRPEAGSEDYQPHGVTSRNILTHKDVTENLETQVVESRLREPPGAKDANGSTR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CREB3L4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  AIBZIP Protein (NBP1-90205PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for AIBZIP Antibody - BSA Free

• AIbZIP
• AIBZIPcAMP-responsive element-binding protein 4
• Androgen-induced basic leucine zipper protein
• ATCE1JAL
• Attaching to CRE-like 1
• cAMP responsive element binding protein 1
• cAMP responsive element binding protein 3-like 4
• CREB3
• CREB4CREB-4
• cyclic AMP-responsive element-binding protein 3-like protein 4
• Cyclic AMP-responsive element-binding protein 4
• hJALcAMP-responsive element-binding protein 3-like protein 4
• tisp40
• Transcript induced in spermiogenesis protein 40

Background

Androgen-induced basic leucine zipper (AIBZIP)is a transcription factor. AIbZIP is a 395 aa protein with homology to cyclic AMP-responsive element binding protein/activating transcription factor. It contains an NH(2)-terminal activation domain, a central bZIP domain, and a COOH-terminal transmembrane domain. Immunoreactive AIbZIP protein has been detected in the cytoplasm of prostatic luminal epithelial cells; full-length AIbZIP-GFP fusion proteins are localized in the cytoplasm of LNCaP cells, while a truncated form of AIbZIP lacking the putative transmembrane domain was exclusively nuclear. AIbZIP is expressed at higher levels in cancerous prostate cells compared with noncancerous prostate cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CREB3L4