AGPAT6 Antibody [mFluor Violet 450 SE]

Product Discontinued

AGPAT6 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: 1-acylglycerol-3-phosphate O-acyltransferase 6(lysophosphatidic acid acyltransferase, zeta). (Uniprot# Q86UL3)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AGPAT6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for AGPAT6 Antibody [mFluor Violet 450 SE]

• 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acidacyltransferase, zeta)
• Acyl-CoA:glycerol-3-phosphate acyltransferase 4
• DKFZp586M1819,1-acyl-sn-glycerol-3-phosphate acyltransferase zeta
• EC 2.3.1.15
• glycerol-3-phosphate acyltransferase 4,1-AGP acyltransferase 6
• glycerol-3-phosphate acyltransferase 6,1-AGPAT 6
• GPAT4,1-acylglycerol-3-phosphate O-acyltransferase 6
• LPAAT-zetaLPAATZ
• Lysophosphatidic acid acyltransferase zeta
• testis spermatogenesis apoptosis-related protein 7
• TSARG7

Background

Glycerol-3-phosphate acyltransferase 4 (GPAT4), also known as AGPAT6, is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland.

Agpat6 deficiency leads to a reduction in body weight and resistance to both diet-induced and genetically induced obesity. This reduced body weight is associated with increased energy expenditure, reduced triglyceride accumulation in BAT and WAT, reduced white adipocyte size, and lack of adipose tissue in the subdermal region. AGPAT6 fills a unique role in determining triglyceride content and composition in adipose tissue and liver that cannot be compensated by other members of the Agpat family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AGPAT6