Adenosine A3 R Antibody

Images

 
Western Blot: Adenosine A3 R Antibody [NLS689] - EGFR and adenosine signaling pathways are involved in CD73-dependent EMT in HNSCC cells (A) CAL27 cells were treated with siRNA targeting CD73 or control siRNA followed ...read more
Immunohistochemistry-Paraffin: Adenosine A3 R Antibody [NLS689] - Analysis of anti-Adenosine A3 Receptor / ADORA3 antibody with human tonsil, squamous epithelium at dilution 20-30 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Po, Ca, Eq, Pm, Pm, Ma-OpSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Adenosine A3 R Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human Adenosine A3 R.
Epitope
3rd cytoplasmic domain
Specificity
Human ADORA3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Opossum (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADORA3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 20-30 ug/ml
Application Notes
Use in IHC and WB reported in scientific literature (PMID: 27557512). Use in ICC/IF reported in scientific literature (PMID: 30641086).
Publications
Read Publications using
NLS689 in the following applications:

  • 2 publications
  • IHC
    1 publication
  • WB
    1 publication

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 30641086). Predicted cross-reactivity based on sequence identity: Marmoset (100%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Adenosine A3 R Antibody

  • A3AR
  • AD026
  • Adenosine A3 R
  • adenosine A3 receptor
  • Adenosine A3R
  • adenosine receptor A3
  • ADORA3
  • bA552M11.5

Background

A3 Adenosine Receptor is a widely expressed receptor that mediates the multiple functions of adenosine. For example, this receptor is believed to mediate the protective effect of adenosine released during cardiac ischemia. In lungs, the receptor mediates inhibition of eosinophil chemotaxis and may be useful in the treatment of eosinophil-dependent diseases such as asthma and rhinitis. Adenosine A3 Receptor has been reported mostly in brain, lung, liver, heart, kidney, and testis. ESTs have been isolated from heart/melanocyte/uterus, kidney, pituitary, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ICC/IF, IHC, IHC-P

Publications for Adenosine A3 R Antibody (NLS689)(3)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, IHC, WB.


Filter By Application
ICC/IF
(2)
IHC
(1)
WB
(1)
All Applications
Filter By Species
Human
(2)
Mouse
(1)
All Species
Showing Publications 1 - 3 of 3.
Publications using NLS689 Applications Species
Ren ZH, Lin CZ, Cao W et al. CD73 is associated with poor prognosis in HNSCC. Oncotarget. Sep 20 2016 [PMID: 27557512] (WB, IHC, Human) WB, IHC Human
Kutryb-Zajac B, Jablonska P, Serocki M et al. Extracellular Adenine Nucleotide and Adenosine Metabolism in Calcific Aortic Valve Disease. bioRxiv Aug 28 2018 (ICC/IF, Human) ICC/IF Human
Kutryb-Zajac B, Mierzejewska P, Sucajtys-Szulc E et al. Inhibition of LPS-stimulated ecto-adenosine deaminase attenuates endothelial cell activation J. Mol. Cell. Cardiol. Jan 11 2019 [PMID: 30641086] (ICC/IF, Mouse) ICC/IF Mouse

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ADORA3
Entrez
Uniprot