ADAM11 Antibody (3D4)

Western Blot: ADAM11 Antibody (3D4) [H00004185-M01] - ADAM11 monoclonal antibody (M01), clone 3D4. Analysis of ADAM11 expression in human colon.

Sandwich ELISA: ADAM11 Antibody (3D4) [H00004185-M01] - Detection limit for recombinant GST tagged ADAM11 is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, S-ELISA
• Clone: 3D4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

ADAM11 Antibody (3D4) Summary

• Immunogen: ADAM11 (NP_002381, 230 a.a. ~ 333 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKEQLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHLFSGR
• Specificity: ADAM11 - ADAM metallopeptidase domain 11
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADAM11
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA 1:100-1:2000
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ADAM11 Antibody (3D4)

• a disintegrin and metalloproteinase domain 11
• ADAM metallopeptidase domain 11
• disintegrin and metalloproteinase domain-containing protein 11
• MDCADAM 11
• Metalloproteinase-like, disintegrin-like, and cysteine-rich protein

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADAM11
• Entrez:
  • 4185(Human)
• OMIM:
  • 155120(Human)
• Uniprot:
  • NP_002381(Human)