Activin C/Inhibin beta C Antibody [Unconjugated]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Activin C/Inhibin beta C Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant mouse Activin C peptide
  aa 236-352
• Specificity: Detects mouse Activin C beta C subunit in direct ELISAs and Western blots. In direct ELISA, approximately 5% cross-reactivity with recombinant human (rh) Activin A and rhInhibin A is observed and no cross-reactivity with rhInhibin B is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: INHBC
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Activin C/Inhibin beta C Antibody [Unconjugated]

• inhibin beta C chain
• Activin C
• IHBC
• INHBC
• inhibin, beta C

Background

Activins belong to the TGF-beta superfamily. They are homo- or heterodimers of activin  beta subunits. At least four mammalian beta subunits, A, B, C, and E, have been described. The beta _c subunit homodimerizes to form Activin CC. A naturally occuring Activin AC heterodimer has also been reported (1).

1. Mellor, S. et al. (2003) Endocrinology 144:4410.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Activin C/Inhibin beta C Antibody (AF489)(1)

Publication using AF489

Bioinformatics

• Gene Symbol: INHBC