ABP1/AOC1 Antibody

Images

 
Western Blot: ABP1/AOC1 Antibody [NBP1-58006] - Antibody Titration: 1 ug/ml Positive control: HepG2 cell lysate.
Immunohistochemistry-Paraffin: ABP1/AOC1 Antibody [NBP1-58006] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

ABP1/AOC1 Antibody Summary

Immunogen
Synthetic peptides corresponding to ABP1(amiloride binding protein 1 (amine oxidase (copper-containing))) The peptide sequence was selected from the C terminal of ABP1 (NP_001082). Peptide sequence QFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNF.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This is a rabbit polyclonal antibody against ABP1 and was validated on Western Blot and immunohistochemistry-paraffin
Theoretical MW
83 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP1-58006.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS & 2% Sucrose.
Preservative
No Preservative
Purity
Immunogen affinity purified
Reconstitution Instructions
Centrifuge prior to opening. Reconstitute with sterilized PBS to a final concentration of 1mg/ml. Vortex followed by Centrifuge again to pellet the solution.

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for ABP1/AOC1 Antibody

  • ABP
  • ABP1
  • amiloride binding protein 1 (amine oxidase (copper-containing))
  • Amiloride-binding protein
  • amiloride-sensitive amine oxidase [copper-containing]
  • amiloride-sensitive amine oxidase
  • AOC1
  • AOC1DAOamiloride-binding protein-1
  • DAO
  • DAO1
  • Diamine Oxidase
  • EC 1.4.3
  • EC 1.4.3.22
  • Histaminase
  • KAO
  • Kidney amine oxidase

Background

ABP1 is a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ABP1/AOC1 Antibody (NBP1-58006)(1)


Showing Publication 1 - 1 of 1.
Publication using NBP1-58006 Applications Species
Boomsma, F. Diabetologia 48 (5), 1002-1007. 2005 [PMID: 15830186]

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Bioinformatics

Gene Symbol ABP1
Entrez
Uniprot