ABCB5 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: ABCB5 Antibody [NBP1-77689] - ABCB5 antibody was tested in A431 cells with FITC (green). Nuclei were counterstained with DAPI (blue).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.11 mg/ml

ABCB5 Antibody Summary

Immunogen
A synthetic peptide made to an internal portion of the human ABCB5 protein (between residues 450-500) [UniProt Q2M3G0]
Localization
Cell membrane; Multi-pass membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABCB5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:100
Application Notes
This ABCB5 antibody is useful for Immunocytochemistry/Immunofluorescence.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1.11 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ABCB5 Antibody

  • ABCB5 P-gp
  • ABCB5
  • ABCB5alpha
  • ABCB5beta
  • ATP-binding cassette protein
  • ATP-binding cassette sub-family B member 5
  • ATP-binding cassette, sub-family B (MDR/TAP), member 5
  • EC 3.6.3
  • EC 3.6.3.44
  • EST422562
  • P-glycoprotein ABCB5

Background

The ATP-binding cassette sub-family B member 5 (ABCB5) is an ABC transporter and PGP member. It is highly expressed in skin and in malignant melanoma. When two abnormal growths of tissues occur, resulting in multiple malignancies, ABCB5 is often highly expressed. This elevated expression in tumor cells can indicate a propensity towards therapeutic failure in many cases. Analysis of ABCB5 concentrations in tumors has been suggested as a fairly dependable qualitative biomarker for assessing the malignancy of melanomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

View specific protocols for ABCB5 Antibody (NBP1-77689): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for ABCB5 Antibody (NBP1-77689) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-77689AF405
Alexa Fluor 488 Labeled NBP1-77689AF488
Alexa Fluor 647 Labeled NBP1-77689AF647
Alexa Fluor 700 Labeled NBP1-77689AF700
Biotin Labeled NBP1-77689B
DyLight 405 Labeled NBP1-77689V
DyLight 488 Labeled NBP1-77689G
DyLight 550 Labeled NBP1-77689R
DyLight 650 Labeled NBP1-77689C

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Bioinformatics

Gene Symbol ABCB5
Entrez
Uniprot