ABCB5 Products

Description

ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.

Bioinformatics

Entrez	340273 Human
Uniprot	AAW31630 Human NP_848654.3 Human Q2M3G0 Human
Product By Gene ID	340273
Alternate Names	ABCB5 P-gp ABCB5alpha ABCB5beta ATP-binding cassette protein ATP-binding cassette sub-family B member 5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 EC 3.6.3 EC 3.6.3.44 EST422562 P-glycoprotein ABCB5

Research Areas for ABCB5

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Lipid and Metabolism