ABCA3 Antibody - BSA Free

Immunohistochemistry-Paraffin: ABCA3 Antibody [NBP1-89310] - Analysis in human lung and cervix, uterine tissues using NBP1-89310 antibody. Corresponding ABCA3 RNA-seq data are presented for the same tissues.

Immunocytochemistry/Immunofluorescence: ABCA3 Antibody [NBP1-89310] - Staining of human cell line HUVEC TERT2 shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.

Immunohistochemistry-Paraffin: ABCA3 Antibody [NBP1-89310] - Staining of human liver shows weak cytoplasmic positivity in hepatocytes.

Immunohistochemistry-Paraffin: ABCA3 Antibody [NBP1-89310] - Staining of human lung shows strong positivity in pneumocytes.

Immunohistochemistry-Paraffin: ABCA3 Antibody [NBP1-89310] - Staining of human cerebellum shows positivity in Purkinje cells.

• Reactivity: Hu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ABCA3 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: MLRLTLGEYGRTVVPFSVPGTSQLGQQLSEHLKDALQAEGQEPREVLGDLEEFLIFRASVEGGGFNERCLVAASFRDVGERTVVNALFNNQAYHSPATALAVVDNLLFKLLCGPHASIVVSNFPQPRSALQAAKDQFNEG
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ABCA3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  ABCA3 Protein (NBP1-89310PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (85%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for ABCA3 Antibody - BSA Free

• ABC transporter 3
• ABC3MGC72201
• ABC-C transporter
• ABC-C
• ATP-binding cassette 3
• ATP-binding cassette sub-family A member 3
• ATP-binding cassette transporter 3
• ATP-binding cassette, sub-family A (ABC1), member 3
• EC 3.6.3
• EC 3.6.3.17
• EST111653
• LBM180
• MGC166979
• SMDP3

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC)transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes aredivided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of theABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellulareukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics andengulfment during programmed cell death. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABCA3