4-1BB Ligand/TNFSF9 Antibody (AP-MAB0875)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications B/N, Flow, IHC, IHC-Fr, IP, CyTOF-ready
Clone
AP-MAB0875
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

4-1BB Ligand/TNFSF9 Antibody (AP-MAB0875) Summary

Immunogen
BALB/c mouse B lymphoma cell line
Specificity
This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with BALB/c mouse B lymphoma cell line.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
TNFSF9
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Blocking/Neutralizing 50-200 molar excess
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • CyTOF-ready
Application Notes
Blocking the binding of soluble 4-1BB to 4-1BBL in vitro. Endotoxin level testing shows extremely low level of LPS (< 0.002EU/ug IgG)

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS - Azide free
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for 4-1BB Ligand/TNFSF9 Antibody (AP-MAB0875)

  • 41BB Ligand
  • 4-1BB Ligand
  • 4-1BBL
  • 4-1BB-L
  • CD137L
  • homolog of mouse 4-1BB-L
  • receptor 4-1BB ligand
  • TNFSF9
  • tumor necrosis factor (ligand) superfamily, member 9
  • tumor necrosis factor ligand superfamily member 9

Background

4-1BBL, is also known as CDw137L, a 97 kD member of the TNF superfamily present on antigen-presenting cells (dendritic cells and macrophages) and activated B and T lymphocytes. 4-1BBL interacts with 4-1BB (CDw137) to induce T and B cell co-stimulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFSF9
Entrez
Uniprot