4-1BB Ligand/TNFSF9 Products

Antibodies
4-1BB Ligand/TNFSF9 Antibody ...
4-1BB Ligand/TNFSF9 Antibody [Unco...
AF2295
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
4-1BB Ligand/TNFSF9 Antibody ...
4-1BB Ligand/TNFSF9 Antibody [Unco...
AF1246
Species: Mu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
4-1BB Ligand/TNFSF9 Antibody ...
4-1BB Ligand/TNFSF9 Antibody (2822...
MAB2295
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Mouse Monoclonal
Antibody Pairs
4-1BB Ligand/TNFSF9 Antibody ...
4-1BB Ligand/TNFSF9 Antibody Pair
H00008744-AP41
Species: Hu
Applications: S-ELISA
Lysates
4-1BB Ligand/TNFSF9 Overexpre ...
4-1BB Ligand/TNFSF9 Overexpression...
NBL1-17171
Applications: WB
Proteins
Recombinant Human 4-1BB Ligan ...
Recombinant Human 4-1BB Ligand/TNF...
NBP2-34959
Species: Hu
Applications: Func, PAGE
Recombinant Mouse 4-1BB Ligan ...
Recombinant Mouse 4-1BB Ligand/TNF...
NBP2-26580
Species: Mu
4-1BB Ligand/TNFSF9 Recombina ...
4-1BB Ligand/TNFSF9 Recombinant Pr...
NBP2-56103PEP
Species: Hu
Applications: AC
RNAi
4-1BB Ligand/TNFSF9 RNAi
4-1BB Ligand/TNFSF9 RNAi
H00008744-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

CD137 exists on the cell surface as a monomer with a molecular mass of 30 kDa and as a dimer of 55 kDa. Human and mouse CD137 share 60% amino acid identity. CD137 (4-1BB), a member of the tumor necrosis factor receptor superfamily, is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. The functions of CD137 in T lymphocytes include regulating activation, proliferation and apoptosis. CD137 and CD28 are costimulatory molecules of T cell activation. Costimulatory molecules are important in initiating anti-tumor immune responses. CD137 plays an important role in regulating T-cell-dependent immune responses. Expression of CD137 correlates negatively with lymphocyte proliferation and positively with the degree of activation-induced cell death caused by mitogen over stimulation. In monocytes, CD137 induces activation, promotes adherence and prolongs survival.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Mouse
Product By Gene ID 8744
Alternate Names
  • tumor necrosis factor ligand superfamily member 9
  • 4-1BB ligand
  • receptor 4-1BB ligand
  • 4-1BBL
  • homolog of mouse 4-1BB-L
  • 4-1BB-L
  • CD137L
  • tumor necrosis factor (ligand) superfamily, member 9

Research Areas for 4-1BB Ligand/TNFSF9

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for 4-1BB Ligand/TNFSF9

Learn more about PTMs related to 4-1BB Ligand/TNFSF9.

Phosphorylation
Biotinylation
Methylation

Bioinformatics Tool for 4-1BB Ligand/TNFSF9

Discover related pathways, diseases and genes to 4-1BB Ligand/TNFSF9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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