ZNF521 Antibody [HRP]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: HRP

ZNF521 Antibody [HRP] Summary

• Immunogen: Antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZNF521. The immunogen is located within the first 50 amino acids of ZNF521. Amino Acid Squence: KKRPEDGEELEDEAVHS
• Specificity: ZNF521 antibody is human specific.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ZNF521
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse: (88%)

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Peptide affinity purified

Alternate Names for ZNF521 Antibody [HRP]

• EHZF
• Evi3
• LIP3
• ZFP521
• zinc finger protein 263
• Zinc finger protein FPM315
• Zinc finger protein with KRAB and SCAN domains 12

Background

Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ZNF521