ZNF198 Antibody - Azide and BSA Free

Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284] - Immunochemical staining of human ZNF198 in human breast carcinoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284] - Immunochemical staining of human ZNF198 in human brain with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

ZNF198 Antibody - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with A synthetic peptide corresponding to the C-terminus of the human ZNF198.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ZMYM2
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:1000-1:4000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Antigen and protein A Affinity-purified

Alternate Names for ZNF198 Antibody - Azide and BSA Free

• FIMRAMPSCLL
• Fused in myeloproliferative disorders protein
• MYM
• Rearranged in atypical myeloproliferative disorder protein
• Zinc finger protein 198rearranged in an atypical myeloproliferative disorder
• zinc finger, MYM-type 2
• ZNF198zinc finger MYM-type protein 2

Background

Official Gene Symbol: ZMYM2 Gen Bank Accession Number: NP_932072 Gene ID: 7750 (Human) Gene Map Locus: 13q11-q12 (Human) ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ZMYM2