ZNF198 Products

Description

ZNF198 contains nine MYM-type zinc fingers. The N-terminal half of the ZNF198 gene has been identified as a gene fused to the cytoplasmic domain of the fibroblast growth factor receptor (FGFR1) gene as a result of a t(8;13) (p11;q11-12) chromosomal rearrangement. The t(8;13) chromosomal translocation is associated with myeloproliferative diseases such as stem cell leukemia lymphoma syndrome (SCLL). Studies of the normal function of ZNF198 have revealed that it associates with HHR6 and RAD18 and may be involved in the repair of DNA. ZNF198 has also been found to associate with the BHC110 subunit of a histone-deacetylase containing corepressor complex and may have an additional function in transcriptional repression. Alternate names for ZNF198 include zinc-finger MYM-type protein 2, fused in myeloproliferative disorders protein, ZMYM2, FIM, RAMP, and SCLL.

Bioinformatics

Entrez	7750 Human
Uniprot	NP_003444.1 Human
Product By Gene ID	7750
Alternate Names	FIMRAMPSCLL Fused in myeloproliferative disorders protein MYM Rearranged in atypical myeloproliferative disorder protein Zinc finger protein 198rearranged in an atypical myeloproliferative disorder zinc finger, MYM-type 2 ZNF198zinc finger MYM-type protein 2