ZEB2 Antibody (2D12)

Western Blot: ZEB2 Antibody (2D12) [H00009839-M03] - Analysis of ZFHX1B expression in Hela S3 NE (Cat # L013V3).

Immunocytochemistry/Immunofluorescence: ZEB2 Antibody (2D12) [H00009839-M03] - Analysis of monoclonal antibody to ZFHX1B on HeLa cell. Antibody concentration 10 ug/ml

Product Discontinued

ZEB2 Antibody (2D12) Summary

• Immunogen: ZFHX1B (NP_055610.1, 1115 a.a. ~ 1214 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ZEB2
• Purity: Ascites

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:100 - 1:2000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ZEB2 Antibody (2D12)

• HSPC082
• KIAA0569FLJ42816
• SIP1
• SIP1HSPC082
• Smad-interacting protein 1
• SMADIP1
• SMADIP1ZFHX1BSIP-1
• ZEB2
• ZFHX1B
• ZFX1B
• zinc finger E-box binding homeobox 2
• zinc finger E-box-binding homeobox 2
• zinc finger homeobox 1b
• Zinc finger homeobox protein 1b

Background

The ZEB2 gene (also known as SIP1 and SMADIP1) is a member of the delta-EF1 (ZEB1; MIM 189909)/Zfh1 family of 2-handed zinc finger/homeodomain proteins. SMADIP1 interacts with receptor-mediated, activated full-length SMADs (see MIM 605568) (Verschueren et al., 1999 [PubMed 10400677]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ZEB2 (H00009839-M03)(3)

Publications using H00009839-M03

• Ohshima, J;Wang, Q;Fitzsimonds, ZR;Miller, DP;Sztukowska, MN;Jung, YJ;Hayashi, M;Whiteley, M;Lamont, RJ; Streptococcus gordonii programs epithelial cells to resist ZEB2 induction by Porphyromonas gingivalis Proc. Natl. Acad. Sci. U.S.A. 2019-04-23 [PMID: 30971493] (WB, Human)
• Konradi S, Yasmin N, Haslwanter D et al. Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2. Eur J Immunol. 2013-12-02 [PMID: 24165969]
• Pogribny IP, Muskhelishvili L, Tryndyak VP, Beland FA. The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation. Toxicol Appl Pharmacol. 2008-12-12 [PMID: 19167416]

Bioinformatics

• Gene Symbol: ZEB2