Ymer Antibody

Western Blot: Ymer Antibody [NBP2-24483] - analysis of Chromosome 3 open reading frame 6 (YMER) in human skeletal muscle lysate in the 1) absence, 2) presence of immunizing peptide, 3) mouse skeletal muscle and 4) rat skeletal muscle lysate using this antibody. 05 ug/ml,0.25 ug/ml and 0.25 ug/ml respectively.

• Reactivity: Hu, Pm, Pm, RM
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

Ymer Antibody Summary

• Description: Novus Biologicals Rabbit Ymer Antibody (NBP2-24483) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide made to the C-terminal portion of human Chromosome 3 open reading frame 6 (YMER) [UniProt Q8IVM0].
• Predicted Species: Chimpanzee (100%), Rhesus Macaque (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCDC50
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.05-0.5 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Ymer Antibody

• C3orf6deafness, autosomal dominant 44
• coiled-coil domain containing 50
• coiled-coil domain-containing protein 50
• DFNA44
• Protein Ymer
• Ymer

Background

Ymer encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCDC50
• Uniprot:
  • Q8IVM0(Human)