XRCC1 Antibody (33-2-5)

Images

 
Western Blot: XRCC1 Antibody (33-2-5) [NB120-1838] - Analysis of LS174T Cells.
Immunohistochemistry-Paraffin: XRCC1 Antibody (33-2-5) [NB120-1838] - Rat testis stained with XRCC1 using peroxidase-conjugate and AEC chromogen. Note nuclear staining of spermatocytes.
Immunohistochemistry: XRCC1 Antibody (33-2-5) [NB120-1838] - Formalin-fixed, paraffin-embedded human testis stained with XRCC1 using peroxidase-conjugate and AEC chromogen. Note nuclear staining of spermatocytes.
Immunoprecipitation: XRCC1 Antibody (33-2-5) [NB120-1838] - Analysis of XRCC1.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, IHC, IHC-P, IP
Clone
33-2-5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

XRCC1 Antibody (33-2-5) Summary

Immunogen
Recombinant human XRCC1 protein
Localization
Nuclear
Specificity
This is specific for XRCC1 (85 kDa).
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
XRCC1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 - 2 ug/ml
  • Immunohistochemistry 1 - 2 ug/ml
  • Immunohistochemistry-Paraffin 1 - 2 ug/ml
  • Immunoprecipitation 2 ug/ml
Positive Control
XRCC1 Lysate (NBL1-17913)
Testis Lysate (NB820-59266)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4) and 0.2% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A purified

Alternate Names for XRCC1 Antibody (33-2-5)

  • DNA repair protein XRCC1
  • RCC
  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • X-ray repair cross-complementing protein 1
  • X-ray-repair, complementing defective, repair in Chinese hamster

Background

XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. In testis XRCC1 is expressed at high levels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for XRCC1 Antibody (NB120-1838) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol XRCC1
Entrez
Uniprot