VPS4B Antibody [Janelia Fluor® 646]

Product Discontinued

VPS4B Antibody [Janelia Fluor® 646] Summary

• Immunogen: vacuolar protein sorting 4 homolog B. (Uniprot# O75351)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: VPS4B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for VPS4B Antibody [Janelia Fluor® 646]

• Cell migration-inducing gene 1 protein
• Protein SKD1
• SKD1B
• SKD1cell migration-inducing 1
• Suppressor of K(+) transport growth defect 1
• suppressor of K+ transport defect 1
• vacuolar protein sorting 4 homolog B (S. cerevisiae)
• vacuolar protein sorting 4B (yeast)
• vacuolar protein sorting 4B
• vacuolar protein sorting-associated protein 4B
• VPS42
• VPS4-2

Background

VPS4B is encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VPS4B