VprBP Antibody

Images

 
Western Blot: VprBP Antibody [NBP2-27203] - analysis of VPRBP using VPRBP antibody. Human brain tissue lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of VPRBP antibody. I goat ...read more
Flow Cytometry: VprBP Antibody [NBP2-27203] - Intracellular analysis of VPRBP in human HeLa and mouse RAW cells using VPRBP antibody at 0.2 ug/10^6 cells. Red represents cells with VPRBP antibody, green represents ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Ch, ChHa, Eq, Fe, Gp, Ma-Op, Pm, Rb, Bv, Pm-OrSpecies Glossary
Applications WB, Flow
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

VprBP Antibody Summary

Immunogen
A portion of amino acids 935-985 from human VPRBP was used as the immunogen for this antibody.
Predicted Species
Orangutan (100%), Bovine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VPRBP
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2-4ug/ml~
  • Flow Cytometry 0.2ug/10^6cells

Reactivity Notes

The amino acid sequence used as immunogen for this antibody is 100% homologous in White-cheeked Gibbon, and 88% homolgous in western clawed Frog.There are numerous isoforms including 1505, 1504, 1076 and 783 amino acids.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for VprBP Antibody

  • DCAF1DDB1 and CUL4 associated factor 1
  • DDB1- and CUL4-associated factor 1
  • HIV-1 Vpr-binding protein
  • KIAA0800protein VPRBP
  • MGC102804
  • RIP
  • Vpr (HIV-1) binding protein
  • Vpr-binding protein
  • VprBP
  • Vpr-interacting protein

Background

VPRBP binds and bridges the CUL4 and DDB1 ubiquitin ligase complex, binding the DNA damage binding protein DDB1 and CUL4. VPRBP is the acronym for the human immunodeficiency virus type-1 Vpr binding protein (1-3). CUL4 is a cullin family memember. Cullins are ubiquitin ligases that are cable of ubiquitinylating a wide range of protein substrates (4). All ubiquitin ligases are important as the modification of proteins by ubiquitin addition modifies or activates functionality (4, 5). VPRBP is critical for normal cell cycle progression through S phase and allows proper cell proliferation and development. VPRBP appears to serve in an epigenetic role through regulation of histone methylation (5). VPRBP antibody provides a reagent for exploration of ubiqitin ligase activities in cell cycle and other cell pathways responsible for normal cell growth and function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-77077
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P, IF, KD
NB100-56583
Species: Hu, Rt, Rb
Applications: WB, Flow, IHC, IHC-P, KO
NB100-56116
Species: Hu, Mu, Rt, Ma
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NB100-56173
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
MAB7047
Species: Hu
Applications: WB, ICC
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, ICC/IF, IHC, IHC-P
AF2658
Species: Hu
Applications: WB, IHC, ICC
NB100-56144
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, IP
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Flow-IC
NBP1-77299
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, GS, KD, KO
NBP2-45041
Species: Hu, Po
Applications: Flow, ICC/IF, IF
NB100-56708
Species: Hu, Mu, Rt, Po, Ch, ChHa, Ma
Applications: WB, Simple Western, EM, Flow, HEStain, IB, ICC/IF, IHC, IHC-Fr, IHC-P, CyTOF-ready, IHC-FrFl, KD, KO
H00008837-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
NBP2-27203
Species: Hu, Mu, Rt, Po, Ch, ChHa, Eq, Fe, Gp, Ma-Op, Pm, Rb, Bv, Pm-Or
Applications: WB, Flow
Supplier Logo

Publications for VprBP Antibody (NBP2-27203) (0)

There are no publications for VprBP Antibody (NBP2-27203).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for VprBP Antibody (NBP2-27203) (0)

There are no reviews for VprBP Antibody (NBP2-27203). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for VprBP Antibody (NBP2-27203) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional VprBP Products

Array NBP2-27203

Bioinformatics Tool for VprBP Antibody (NBP2-27203)

Discover related pathways, diseases and genes to VprBP Antibody (NBP2-27203). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for VprBP Antibody (NBP2-27203)

Discover more about diseases related to VprBP Antibody (NBP2-27203).
 

Pathways for VprBP Antibody (NBP2-27203)

View related products by pathway.

PTMs for VprBP Antibody (NBP2-27203)

Learn more about PTMs related to VprBP Antibody (NBP2-27203).

Blogs on VprBP

There are no specific blogs for VprBP, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our VprBP Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol VPRBP
Uniprot