VLDLR Antibody (rVLDLR/1337) [Alexa Fluor™ Plus 488]

• Reactivity: Hu, Rt
• Applications: IHC
• Clone: rVLDLR/1337
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

VLDLR Antibody (rVLDLR/1337) [Alexa Fluor™ Plus 488] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant human VLDLR fragment from c-terminal (Uniprot: P98155)
• Localization: Cytoplasmic
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: VLDLR
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for VLDLR Antibody (rVLDLR/1337) [Alexa Fluor™ Plus 488]

• CARMQ1
• CHRMQ1
• FLJ35024
• very low density lipoprotein receptor
• very low-density lipoprotein receptor
• VLDL R
• VLDL receptor
• VLDLR
• VLDL-R
• VLDLRCH

Background

VLDL (very low density lipoprotein) cholesterol is one of the three major types of cholesterol found in blood. VLDL receptor plays an essential role in triglyceride metabolism. It binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VLDLR